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Relative replication capacity of phenotypic SIV variants during primary infections differs with route of infection |
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Τρίτη, 12 Οκτώβριος 2010 17:00 |
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Conclusions:
These results suggest that the capacity to replicate in CD4+ T cells is a significant determinant of SIV fitness and pathogenicity. Furthermore, the data also suggest that mucosal transmission may support early replication of phenotypically diverse variants, while slowing the rate of CD4+ T cell decline during the initial stages of infection. (Source: Retrovirology)
Source: www.medworm.com
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