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The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein |
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Τρίτη, 12 Οκτώβριος 2010 17:00 |
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Conclusion:
Within the limitations of this experimental system, BAX-dependent apoptosis in HCT116 cells exhibits an all-or-none response depending on the level of BAX protein present. The lack of BAX aggregation at sub-saturation levels suggests that the translocation step of BAX activation may be impaired. (Source: BMC Cancer)MedWorm Message: Watch the new MedWorm demo and find out how to get all the very latest, relevant, organized information daily!
Source: www.medworm.com
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